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Through the clinical use of trichuris suis and other helminths for crohn’s disease (cd). Long-lived helminthic parasites are remarkable in their ability to down-regulate host immunity, protecting themselves from elimination, and also minimize severe pathological host changes. This review summarizes what is known about the underlying mechanisms that may account for the observed patterns in humans treated with helminths for cd. The th2 arm of the immune system is emphasized as a component of primary importance in the association between the host immune system and gi nematode infections. Although gi nematode infections in humans cause significant morbidity and mortality, the existence and nature of protective mechanisms these helminths may confer remain largely unclear. Please contact us for the full text of this article. Or, you can access it here (payment required to access full text): springerlink (parasitology research) helminths as therapeutic agents (helminthic therapy) for inflammatory bowel disease abstract over the last decade major advances have been made in our understanding of the mechanisms and mediators of inflammation that hold the promise of the development of new therapies for inflammatory disease. While much is to be gleaned from the application of new technologies, assessment of the age-old host–parasite relationship may also provide insights on how to counter pathological inflammatory events. In the case of inflammatory bowel disease [particularly crohn’s disease, which is associated with t helper 1 (th1) events] it is proposed that infection with parasitic helminths would be beneficial: the paradigm being that of immune deviation, where th2 cytokines mobilized in response to the helminth will prevent or antagonize the disease-promoting th1 events in the gut. The situation is unlikely to be this simple. Here we review and critique the data in support of helminth therapy for inflammatory bowel disease, drawing attention to the gaps in knowledge and presenting a view on how the field may be adva. viagra discount viagra for sale viagra for sale buy viagra online cheap viagra viagra for sale cheap generic viagra viagra online Excellent Value of Installers

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